STRUCTURAL AND FUNCTIONAL CHANGES OF THE HEART AND VASCULATURE DURING AGING:

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CLINICAL SIGNIFICANCE OF DIASTOLIC DYSFUNCTION AND ARTERIAL STIFFNESS

Editorial Note

This article was originally published in the journal Zarubezhnaya Meditsina i My in April 2021.
The Editorial Board of the International Journal of Interdisciplinary Research approved the republication of this work due to its interdisciplinary relevance to cardiology, gerontology, and clinical physiology.
The article is reproduced with the author’s permission and without substantive changes to the original content.

Abstract

Aging of the cardiovascular system is accompanied by progressive structural and functional changes in the heart and blood vessels, which substantially contribute to cardiovascular risk in older populations. Among the most clinically significant manifestations of cardiovascular aging are increased arterial stiffness and the development of left ventricular diastolic dysfunction. This article examines the pathophysiological mechanisms underlying age-associated changes in the vascular wall and myocardium, analyzes their interrelationship and clinical significance, and discusses current diagnostic approaches and preventive
perspectives. Particular attention is given to arterial stiffness as an integrative marker of vascular aging and its impact on left ventricular diastolic function.

Keywords:

cardiovascular aging, arterial stiffness, diastolic dysfunction, left ventricle, biological age, cardiogerontology.

Author: Ekaterina R. Alimova, MD
ORCID: 0009-0005-6128-6641

International Journal of Interdisciplinary Research
Volume 2, Issue 2 (2021)

Peer Reviewer (Acknowledged): Boris Karsakov
ORCID: 0009-0006-4851-6366

DOI: pending

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STRUCTURAL_AND_FUNCTIONAL_CHANGES_OF_THE_HEART_AND_VASCULATURE_DURING

References

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